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Which of the following represents the possible genotype(s) resulting from a cross between an individual heterozygous (Bb) and one that is homozygous (bb) ?


A) BB and Bb
B) Bb and bb
C) BB only
D) Bb only
E) bb only

F) A) and B)
G) A) and C)

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A couple who does not have cystic fibrosis but are both heterozygous has already had three girls with cystic fibrosis, and are hoping to have a normal child for their fourth. What are the chances that the fourth child will be a normal male?


A) 0
B) 1/8
C) 1/4
D) 3/8
E) 1/2

F) A) and D)
G) B) and E)

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The probability that two genes will be separated by crossing-over is related to:


A) the phenotype that they control.
B) how far the two genes are from the centromere.
C) the distance between the two genes on the chromosome.
D) whether the two genes are located on a sex chromosome.
E) how far the genes are from the kinetochore.

F) B) and E)
G) D) and E)

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Which of the following represents the possible genotype(s) resulting from a cross between an individual homozygous for black hair (BB) and an individual homozygous for blonde hair (bb) ?


A) BB and Bb
B) BB, Bb, and bb
C) BB only
D) Bb only
E) bb only

F) B) and E)
G) A) and B)

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The presence of two X chromosomes supports the existence of a particular genetic locus. __________________

A) True
B) False

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A lizard with a striped tail and a normal head crossed with one having a normal tail and a spotted head produce all normal (no stripes or spots) F1 progeny. What progeny would be expected to be produced by mating either of the parental lizards with another that had a striped tail and spotted head, if the genes conferring stripes and spots were close together on the same chromosome?


A) equal numbers of normal, striped, spotted and striped, and spotted
B) 3 striped : 1 spotted
C) mostly progeny that are striped or spotted
D) mostly progeny that are normal or striped and spotted
E) 9 normal : 3 striped : 3 spotted : 1 striped and spotted

F) B) and C)
G) None of the above

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The offspring of two heterozygous gray-bodied, normal-winged flies should be 50% gray-bodied/normal wings (BbRr) and 50% black-bodied/vestigial wings (bbrr) because these alleles are linked. Suppose a small number, say 15%, of the offspring are instead black-bodied with normal wings. This is most likely the result of:


A) crossing-over.
B) incomplete dominance.
C) codominance.
D) an error in meiosis.
E) mutation.

F) C) and D)
G) B) and E)

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A brown-eyed couple already has a child with blue eyes. What is the probability that their next child will have blue eyes, assuming that the brown eye allele is dominant and the blue eye allele is recessive?


A) 0
B) 1/4
C) 1/2
D) 3/4
E) 1

F) A) and D)
G) D) and E)

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A gene that affects, prevents, or masks the expression of a gene at another locus is a(n) ____ gene.


A) recessive
B) dominant
C) epistatic
D) codominant
E) pleiotropic

F) B) and D)
G) C) and E)

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An organism with the genotype of AaXx can produce gametes containing ____ if the two genes are unlinked.


A) either Aa or Xx
B) either AX, Ax, aX, ax
C) AaXx only
D) AX or ax
E) A,a,X,x

F) A) and E)
G) A) and D)

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What are the predicted phenotypes of the male children from the union of a woman who is heterozygous for hemophilia and a man who has normal blood clotting characteristics? (Use the Punnett square to verify your answer.)


A) all normal
B) 3 normal : 1 hemophilia
C) 1 hemophilia : 1 normal
D) 1 hemophilia : 3 normal
E) all hemophiliacs

F) A) and B)
G) B) and E)

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C

In a two-point test cross, 36 of the offspring were recombinant types. The remaining 64 offspring were parental types. How many map units separate the two loci?


A) 28
B) 36
C) 64
D) 78
E) 100

F) A) and E)
G) A) and B)

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A Barr body in a mammalian female cell represents a(n) :


A) inactivated oocyte.
B) polar body.
C) degenerate nucleus.
D) inactivated X chromosome.
E) inactivated Y chromosome.

F) A) and D)
G) All of the above

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What are the predicted phenotypes of the female children from the union of a woman who is heterozygous for hemophilia and a man who has normal blood clotting characteristics? (Use the Punnett square to verify your answer.)


A) all carriers
B) 3 homozygous normal : 1 carrier
C) 1 homozygous normal : 1 carrier
D) 1 hemophilia: 2 homozygous; normal : 1 carrier
E) all hemophiliacs

F) D) and E)
G) B) and E)

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C

What is an X-linked inheritance pattern? Use a specific example to explain the role of the father and mother in this unique inheritance pattern and note the differential impact on male and female offspring.

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In X linked inheritance patterns, X linked recessive traits are more common in males than females. A color blind female must have a color blind father and a mother who is either homozygous or heterozygous for the recessive allele for color blindness. Whereas a color blind male need only have a mother who is heterozygous for color blindness.

Mating a pure-bred pink rose plant with a pure-bred pink rose plant will produce:


A) plants with pink, red, and white roses.
B) plants with only pink roses.
C) plants with red or white roses in a 3:1 ratio.
D) plants with white or red roses in a 3:1 ratio.
E) plants with only red roses.

F) D) and E)
G) A) and B)

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A female black cat mated with an albino male and gave birth to 6 black kittens. When the albino male was mated with a different female black cat, 3 black cats and 2 albino cats were produced. How can you explain this genetic situation? Write genotypes for all three parental cats and offspring.

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Concepts to Consider: The first female b...

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The physical location of a particular gene on a chromosome is called:


A) an allele.
B) its locus.
C) a trait.
D) a chromatid.
E) its genotype.

F) A) and B)
G) D) and E)

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In humans, a mutation in the phenylalanine hydroxylase gene causes phenylketonuria (PKU), which is characterized by a wide variety of medical problems. This is an example of epistasis .

A) True
B) False

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Which of the following represents the possible genotype(s) resulting from a cross between one homozygous (BB) individual and one heterozygous (Bb) individual?


A) BB and Bb
B) BB, Bb, and bb
C) BB only
D) Bb only
E) bb only

F) B) and E)
G) B) and D)

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